Systemic Lupus Erythematosus-associated Neutrophil Cytosolic Factor 2 Mutation Affects the Structure of NADPH Oxidase Complex

In a case-control association study with 3716 North Americans of Hispanic descent and 4867 North Americans of European descent, we show that the associations of rs17849502 (NCF2 His-389 → Gln) and rs13306575 (NCF2 Arg-395 → Trp) with systemic lupus erythematosus are independent. We have shown that H...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Armstrong, Don L., Eisenstein, Miriam, Zidovetzki, Raphael, Jacob, Chaim O.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432280/
https://ncbi.nlm.nih.gov/pubmed/25795782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.639021
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