Structural Biology of Presenilins and Signal Peptide Peptidases

द्वारा Tomita, Taisuke, Iwatsubo, Takeshi
प्रकाशित 2013

Extracellular α-synuclein levels are regulated by neuronal activity

द्वारा Yamada, Kaoru, Iwatsubo, Takeshi
में प्रकाशित Mol Neurodegener (2018)

The Emerging Functions of LRRK2 and Rab GTPases in the Endolysosomal System

द्वारा Kuwahara, Tomoki, Iwatsubo, Takeshi
में प्रकाशित Front Neurosci (2020)

The past, present, and future of disease-modifying therapies for Alzheimer’s disease

द्वारा SUZUKI, Kazushi, IWATA, Atsushi, IWATSUBO, Takeshi
में प्रकाशित Proc Jpn Acad Ser B Phys Biol Sci (2017)

Presenilins and γ-Secretase: Structure, Function, and Role in Alzheimer Disease

द्वारा De Strooper, Bart, Iwatsubo, Takeshi, Wolfe, Michael S.
प्रकाशित 2012

Presenilin-dependent intramembrane cleavage of ephrin-B1

द्वारा Tomita, Taisuke, Tanaka, Sayaka, Morohashi, Yuichi, Iwatsubo, Takeshi
प्रकाशित 2006

Seeded Aggregation and Toxicity of α-Synuclein and Tau: CELLULAR MODELS OF NEURODEGENERATIVE DISEASES

द्वारा Nonaka, Takashi, Watanabe, Sayuri T., Iwatsubo, Takeshi, Hasegawa, Masato
प्रकाशित 2010

Contribution of the γ-Secretase Subunits to the Formation of Catalytic Pore of Presenilin 1 Protein

द्वारा Takeo, Koji, Watanabe, Naoto, Tomita, Taisuke, Iwatsubo, Takeshi
प्रकाशित 2012

Characterization of the unique In Vitro effects of unsaturated fatty acids on the formation of amyloid β fibrils

द्वारा Eto, Miki, Hashimoto, Tadafumi, Shimizu, Takao, Iwatsubo, Takeshi
में प्रकाशित PLoS One (2019)

The C-Terminal PAL Motif and Transmembrane Domain 9 of Presenilin 1 Are Involved in the Formation of the Catalytic Pore of the γ-Secretase

द्वारा Sato, Chihiro, Takagi, Shizuka, Tomita, Taisuke, Iwatsubo, Takeshi
में प्रकाशित J Neurosci (2008)

Structure of the Catalytic Pore of γ-Secretase Probed by the Accessibility of Substituted Cysteines

द्वारा Sato, Chihiro, Morohashi, Yuichi, Tomita, Taisuke, Iwatsubo, Takeshi
में प्रकाशित J Neurosci (2006)

Phosphorylation of α-Synuclein Protein at Ser-129 Reduces Neuronal Dysfunction by Lowering Its Membrane Binding Property in Caenorhabditis elegans

द्वारा Kuwahara, Tomoki, Tonegawa, Reina, Ito, Genta, Mitani, Shohei, Iwatsubo, Takeshi
प्रकाशित 2012

Lack of Correlation between the Kinase Activity of LRRK2 Harboring Kinase-Modifying Mutations and Its Phosphorylation at Ser910, 935, and Ser955

द्वारा Ito, Genta, Fujimoto, Tetta, Kamikawaji, Shogo, Kuwahara, Tomoki, Iwatsubo, Takeshi
प्रकाशित 2014

Role of Apolipoprotein E in β-Amyloidogenesis: ISOFORM-SPECIFIC EFFECTS ON PROTOFIBRIL TO FIBRIL CONVERSION OF Aβ IN VITRO AND BRAIN Aβ DEPOSITION IN VIVO

द्वारा Hori, Yukiko, Hashimoto, Tadafumi, Nomoto, Hidetoshi, Hyman, Bradley T., Iwatsubo, Takeshi
में प्रकाशित J Biol Chem (2015)

Role of apolipoprotein E in β-amyloidogenesis: Isoform-specific effects on protofibril to fibril conversion of Aβ in vitro and brain Aβ deposition in vivo.

द्वारा Hori, Yukiko, Hashimoto, Tadafumi, Nomoto, Hidetoshi, Hyman, Bradley T., Iwatsubo, Takeshi
में प्रकाशित J Biol Chem (2018)

Participation of Transmembrane Domain 1 of Presenilin 1 in the Catalytic Pore Structure of the γ-Secretase

द्वारा Takagi, Shizuka, Tominaga, Aya, Sato, Chihiro, Tomita, Taisuke, Iwatsubo, Takeshi
में प्रकाशित J Neurosci (2010)

Imago Mundi, Imago AD, Imago ADNI

द्वारा Villemagne, Victor L, Kim, Seong Yoon, Rowe, Christopher C, Iwatsubo, Takeshi
में प्रकाशित Alzheimers Res Ther (2014)

Conformational Changes in Transmembrane Domain 4 of Presenilin 1 Are Associated with Altered Amyloid-β 42 Production

द्वारा Tominaga, Aya, Cai, Tetsuo, Takagi-Niidome, Shizuka, Iwatsubo, Takeshi, Tomita, Taisuke
में प्रकाशित J Neurosci (2016)

Amyloid Angiopathy and Variability in Amyloid β Deposition Is Determined by Mutation Position in Presenilin-1-Linked Alzheimer’s Disease

द्वारा Mann, David M. A., Pickering-Brown, Stuart M., Takeuchi, Ayano, Iwatsubo, Takeshi
प्रकाशित 2001

Sample Size Estimation for Alzheimer’s Disease Trials from Japanese ADNI Serial Magnetic Resonance Imaging

द्वारा Fujishima, Motonobu, Kawaguchi, Atsushi, Maikusa, Norihide, Kuwano, Ryozo, Iwatsubo, Takeshi, Matsuda, Hiroshi
में प्रकाशित J Alzheimers Dis (2017)