Structural Biology of Presenilins and Signal Peptide Peptidases

অনুযায়ী Tomita, Taisuke, Iwatsubo, Takeshi
প্রকাশিত 2013

Extracellular α-synuclein levels are regulated by neuronal activity

অনুযায়ী Yamada, Kaoru, Iwatsubo, Takeshi
প্রকাশিত Mol Neurodegener (2018)

The Emerging Functions of LRRK2 and Rab GTPases in the Endolysosomal System

অনুযায়ী Kuwahara, Tomoki, Iwatsubo, Takeshi
প্রকাশিত Front Neurosci (2020)

The past, present, and future of disease-modifying therapies for Alzheimer’s disease

অনুযায়ী SUZUKI, Kazushi, IWATA, Atsushi, IWATSUBO, Takeshi
প্রকাশিত Proc Jpn Acad Ser B Phys Biol Sci (2017)

Presenilins and γ-Secretase: Structure, Function, and Role in Alzheimer Disease

অনুযায়ী De Strooper, Bart, Iwatsubo, Takeshi, Wolfe, Michael S.
প্রকাশিত 2012

Presenilin-dependent intramembrane cleavage of ephrin-B1

অনুযায়ী Tomita, Taisuke, Tanaka, Sayaka, Morohashi, Yuichi, Iwatsubo, Takeshi
প্রকাশিত 2006

Seeded Aggregation and Toxicity of α-Synuclein and Tau: CELLULAR MODELS OF NEURODEGENERATIVE DISEASES

অনুযায়ী Nonaka, Takashi, Watanabe, Sayuri T., Iwatsubo, Takeshi, Hasegawa, Masato
প্রকাশিত 2010

Contribution of the γ-Secretase Subunits to the Formation of Catalytic Pore of Presenilin 1 Protein

অনুযায়ী Takeo, Koji, Watanabe, Naoto, Tomita, Taisuke, Iwatsubo, Takeshi
প্রকাশিত 2012

Characterization of the unique In Vitro effects of unsaturated fatty acids on the formation of amyloid β fibrils

অনুযায়ী Eto, Miki, Hashimoto, Tadafumi, Shimizu, Takao, Iwatsubo, Takeshi
প্রকাশিত PLoS One (2019)

The C-Terminal PAL Motif and Transmembrane Domain 9 of Presenilin 1 Are Involved in the Formation of the Catalytic Pore of the γ-Secretase

অনুযায়ী Sato, Chihiro, Takagi, Shizuka, Tomita, Taisuke, Iwatsubo, Takeshi
প্রকাশিত J Neurosci (2008)

Structure of the Catalytic Pore of γ-Secretase Probed by the Accessibility of Substituted Cysteines

অনুযায়ী Sato, Chihiro, Morohashi, Yuichi, Tomita, Taisuke, Iwatsubo, Takeshi
প্রকাশিত J Neurosci (2006)

Phosphorylation of α-Synuclein Protein at Ser-129 Reduces Neuronal Dysfunction by Lowering Its Membrane Binding Property in Caenorhabditis elegans

অনুযায়ী Kuwahara, Tomoki, Tonegawa, Reina, Ito, Genta, Mitani, Shohei, Iwatsubo, Takeshi
প্রকাশিত 2012

Lack of Correlation between the Kinase Activity of LRRK2 Harboring Kinase-Modifying Mutations and Its Phosphorylation at Ser910, 935, and Ser955

অনুযায়ী Ito, Genta, Fujimoto, Tetta, Kamikawaji, Shogo, Kuwahara, Tomoki, Iwatsubo, Takeshi
প্রকাশিত 2014

Role of Apolipoprotein E in β-Amyloidogenesis: ISOFORM-SPECIFIC EFFECTS ON PROTOFIBRIL TO FIBRIL CONVERSION OF Aβ IN VITRO AND BRAIN Aβ DEPOSITION IN VIVO

অনুযায়ী Hori, Yukiko, Hashimoto, Tadafumi, Nomoto, Hidetoshi, Hyman, Bradley T., Iwatsubo, Takeshi
প্রকাশিত J Biol Chem (2015)

Role of apolipoprotein E in β-amyloidogenesis: Isoform-specific effects on protofibril to fibril conversion of Aβ in vitro and brain Aβ deposition in vivo.

অনুযায়ী Hori, Yukiko, Hashimoto, Tadafumi, Nomoto, Hidetoshi, Hyman, Bradley T., Iwatsubo, Takeshi
প্রকাশিত J Biol Chem (2018)

Participation of Transmembrane Domain 1 of Presenilin 1 in the Catalytic Pore Structure of the γ-Secretase

অনুযায়ী Takagi, Shizuka, Tominaga, Aya, Sato, Chihiro, Tomita, Taisuke, Iwatsubo, Takeshi
প্রকাশিত J Neurosci (2010)

Imago Mundi, Imago AD, Imago ADNI

অনুযায়ী Villemagne, Victor L, Kim, Seong Yoon, Rowe, Christopher C, Iwatsubo, Takeshi
প্রকাশিত Alzheimers Res Ther (2014)

Conformational Changes in Transmembrane Domain 4 of Presenilin 1 Are Associated with Altered Amyloid-β 42 Production

অনুযায়ী Tominaga, Aya, Cai, Tetsuo, Takagi-Niidome, Shizuka, Iwatsubo, Takeshi, Tomita, Taisuke
প্রকাশিত J Neurosci (2016)

Amyloid Angiopathy and Variability in Amyloid β Deposition Is Determined by Mutation Position in Presenilin-1-Linked Alzheimer’s Disease

অনুযায়ী Mann, David M. A., Pickering-Brown, Stuart M., Takeuchi, Ayano, Iwatsubo, Takeshi
প্রকাশিত 2001

Sample Size Estimation for Alzheimer’s Disease Trials from Japanese ADNI Serial Magnetic Resonance Imaging

অনুযায়ী Fujishima, Motonobu, Kawaguchi, Atsushi, Maikusa, Norihide, Kuwano, Ryozo, Iwatsubo, Takeshi, Matsuda, Hiroshi
প্রকাশিত J Alzheimers Dis (2017)