TMIC-04. A POTENT MICROGLIAL RESPONSE TO BLOCKING THE CD47-SIRPα ANTI-PHAGOCYTIC AXIS OVERCOMES DEFICIENT MACROPHAGE RECRUITMENT DURING ANTI-CD47 IMMUNOTHERAPY AGAINST GLIOBLASTOMA...

Por Hutter, Gregor, Theruvath, Johanna, Graef, Claus Moritz, Weissman, Irving, Mitra, Siddhartha S, Cheshier, Samuel H
Publicado no Neuro Oncol (2017)

Non-invasive neural stem cells become invasive in vitro by combined FGF2 and BMP4 signaling

Por Sailer, Martin H. M., Gerber, Alexandra, Tostado, Cristóbal, Hutter, Gregor, Cordier, Dominik, Mariani, Luigi, Ritz, Marie-Françoise
Publicado em 2013

SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells

Por Nuvolone, Mario, Kana, Veronika, Hutter, Gregor, Sakata, Daiji, Mortin-Toth, Steven M., Russo, Giancarlo, Danska, Jayne S., Aguzzi, Adriano
Publicado em 2013

ATIM-48 (LTBK-05). MULTIDIMENSIONAL PERSONALIZED RESPONSE ASSESSMENT TO MICROGLIA MODULATORS IN GLIOBLASTOMA BIOREACTORS

Por Shekarian, Tala, Wachnowicz, Anna Theresa, Flammer, Julia, Paganetti, Chiara, Martins, Tomas, Muraro, Manuele, Schürch, Christian Martijn, Hutter, Gregor
Publicado no Neuro Oncol (2019)

PM-08 A HUMANIZED CO-TRANSPLANT XENOGRAFT MOUSE MODEL, TO STUDY TOXICITY OF DRUGS TARGETED AGAINST PEDIATRIC BRAIN TUMORS

Por Gholamin, Sharareh, Kahn, Suzana Assad, Esparza, Rogelio, Hutter, Gregor, Feroze, Abdullah, Weissman, Irving L., Mitra, Siddhartha S., Cheshier, Samuel H.
Publicado no Neuro Oncol (2015)

CBMT-27. PROTEOMIC MAP OF GLIOMA BIOPSIES REVEALS FUNCTIONAL DEFECTS IN ENDOCYTOSIS

Por Boulay, Jean-Louis, Ritz, Marie-Françoise, Hutter, Gregor, Tostado, Cristobal, Buser, Dominik, Spiess, Martin, Frank, Stephan, Jenö, Paul, Mariani, Luigi
Publicado no Neuro Oncol (2018)

Microglia-Centered Combinatorial Strategies Against Glioblastoma

Por Martins, Tomás A., Schmassmann, Philip, Shekarian, Tala, Boulay, Jean-Louis, Ritz, Marie-Françoise, Zanganeh, Steven, vom Berg, Johannes, Hutter, Gregor
Publicado no Front Immunol (2020)

The role of calorie restriction and SIRT1 in prion mediated neurodegeneration

Por Chen, Danica, Steele, Andrew D., Hutter, Gregor, Bruno, Joanne, Govindarajan, Arvind, Easlon, Erin, Lin, Su-Ju, Aguzzi, Adriano, Lindquist, Susan, Guarente, Leonard
Publicado em 2008

An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery

Por Sailer, Martin H. M., Sarvepalli, Durga, Brégère, Catherine, Fisch, Urs, Guentchev, Marin, Weller, Michael, Guzman, Raphael, Bettler, Bernhard, Ghosh, Arkasubhra, Hutter, Gregor
Publicado no J Vis Exp (2016)

Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease

Por Steele, Andrew D., Hutter, Gregor, Jackson, Walker S., Heppner, Frank L., Borkowski, Andrew W., King, Oliver D., Raymond, Gregory J., Aguzzi, Adriano, Lindquist, Susan
Publicado em 2008

Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain–dependent manner

Por Kranich, Jan, Krautler, Nike Julia, Falsig, Jeppe, Ballmer, Boris, Li, Shulei, Hutter, Gregor, Schwarz, Petra, Moos, Rita, Julius, Christian, Miele, Gino, Aguzzi, Adriano
Publicado em 2010

Quantitative proteomics reveals reduction of endocytic machinery components in gliomas

Por Buser, Dominik P., Ritz, Marie-Françoise, Moes, Suzette, Tostado, Cristobal, Frank, Stephan, Spiess, Martin, Mariani, Luigi, Jenö, Paul, Boulay, Jean-Louis, Hutter, Gregor
Publicado no EBioMedicine (2019)

Cross-Reactivity and Functionality of Approved Human Immune Checkpoint Blockers in Dogs

Por Pantelyushin, Stanislav, Ranninger, Elisabeth, Guerrera, Diego, Hutter, Gregor, Maake, Caroline, Markkanen, Enni, Bettschart-Wolfensberger, Regula, Rohrer Bley, Carla, Läubli, Heinz, vom Berg, Johannes
Publicado no Cancers (Basel) (2021)

IDH/MGMT-driven molecular classification of low-grade glioma is a strong predictor for long-term survival

Por Leu, Severina, von Felten, Stefanie, Frank, Stephan, Vassella, Erik, Vajtai, Istvan, Taylor, Elisabeth, Schulz, Marianne, Hutter, Gregor, Hench, Jürgen, Schucht, Philippe, Boulay, Jean-Louis, Mariani, Luigi
Publicado em 2013

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

Por Zanganeh, Saeid, Hutter, Gregor, Spitler, Ryan, Lenkov, Olga, Mahmoudi, Morteza, Shaw, Aubie, Pajarinen, Jukka Sakari, Nejadnik, Hossein, Goodman, Stuart, Moseley, Michael, Coussens, Lisa Marie, Daldrup-Link, Heike Elisabeth
Publicado no Nat Nanotechnol (2016)

PD-1 expression by tumor-associated macrophages inhibits phagocytosis and tumor immunity

Por Gordon, Sydney R., Maute, Roy L., Dulken, Ben W., Hutter, Gregor, George, Benson M., McCracken, Melissa N., Gupta, Rohit, Tsai, Jonathan M., Sinha, Rahul, Corey, Daniel, Ring, Aaron M., Connolly, Andrew J., Weissman, Irving L.
Publicado no Nature (2017)

Anti-CD47 Treatment Stimulates Phagocytosis of Glioblastoma by M1 and M2 Polarized Macrophages and Promotes M1 Polarized Macrophages In Vivo

Por Zhang, Michael, Hutter, Gregor, Kahn, Suzana A., Azad, Tej D., Gholamin, Sharareh, Xu, Chelsea Y., Liu, Jie, Achrol, Achal S., Richard, Chase, Sommerkamp, Pia, Schoen, Matthew Kenneth, McCracken, Melissa N., Majeti, Ravi, Weissman, Irving, Mitra, Siddhartha S., Cheshier, Samuel H.
Publicado no PLoS One (2016)

Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma

Por Hutter, Gregor, Theruvath, Johanna, Graef, Claus Moritz, Zhang, Michael, Schoen, Matthew Kenneth, Manz, Eva Maria, Bennett, Mariko L., Olson, Andrew, Azad, Tej D., Sinha, Rahul, Chan, Carmel, Assad Kahn, Suzana, Gholamin, Sharareh, Wilson, Christy, Grant, Gerald, He, Joy, Weissman, Irving L., Mitra, Siddhartha S., Cheshier, Samuel H.
Publicado no Proc Natl Acad Sci U S A (2019)

Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma

Por Kahn, Suzana A., Wang, Xin, Nitta, Ryan T., Gholamin, Sharareh, Theruvath, Johanna, Hutter, Gregor, Azad, Tej D., Wadi, Lina, Bolin, Sara, Ramaswamy, Vijay, Esparza, Rogelio, Liu, Kun-Wei, Edwards, Michael, Swartling, Fredrik J., Sahoo, Debashis, Li, Gordon, Wechsler-Reya, Robert J., Reimand, Jüri, Cho, Yoon-Jae, Taylor, Michael D., Weissman, Irving L., Mitra, Siddhartha S., Cheshier, Samuel H.
Publicado no Nat Commun (2018)

Publisher Correction: Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma

Por Kahn, Suzana A., Wang, Xin, Nitta, Ryan T., Gholamin, Sharareh, Theruvath, Johanna, Hutter, Gregor, Azad, Tej D., Wadi, Lina, Bolin, Sara, Ramaswamy, Vijay, Esparza, Rogelio, Liu, Kun-Wei, Edwards, Michael, Swartling, Fredrik J., Sahoo, Debashis, Li, Gordon, Wechsler-Reya, Robert J., Reimand, Jüri, Cho, Yoon-Jae, Taylor, Michael D., Weissman, Irving L., Mitra, Siddhartha S., Cheshier, Samuel H.
Publicado no Nat Commun (2018)