Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma

Glioblastoma multiforme (GBM) is a highly aggressive malignant brain tumor with fatal outcome. Tumor-associated macrophages and microglia (TAMs) have been found to be major tumor-promoting immune cells in the tumor microenvironment. Hence, modulation and reeducation of tumor-associated macrophages a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Hutter, Gregor, Theruvath, Johanna, Graef, Claus Moritz, Zhang, Michael, Schoen, Matthew Kenneth, Manz, Eva Maria, Bennett, Mariko L., Olson, Andrew, Azad, Tej D., Sinha, Rahul, Chan, Carmel, Assad Kahn, Suzana, Gholamin, Sharareh, Wilson, Christy, Grant, Gerald, He, Joy, Weissman, Irving L., Mitra, Siddhartha S., Cheshier, Samuel H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338872/
https://ncbi.nlm.nih.gov/pubmed/30602457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721434116
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