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Non-invasive neural stem cells become invasive in vitro by combined FGF2 and BMP4 signaling

Neural stem cells (NSCs) typically show efficient self-renewal and selective differentiation. Their invasion potential, however, is not well studied. In this study, Sox2-positive NSCs from the E14.5 rat cortex were found to be non-invasive and showed only limited migration in vitro. By contrast, FGF...

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Detalhes bibliográficos
Main Authors: Sailer, Martin H. M., Gerber, Alexandra, Tostado, Cristóbal, Hutter, Gregor, Cordier, Dominik, Mariani, Luigi, Ritz, Marie-Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744023/
https://ncbi.nlm.nih.gov/pubmed/23788430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.125757
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