The Role of Apoptosis in the Regulation of Hematopoietic Stem Cells: Overexpression of BCL-2 Increases Both Their Number and Repopulation Potential

Por Domen, Jos, Cheshier, Samuel H., Weissman, Irving L.
Publicado em 2000

In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells

Por Cheshier, Samuel H., Morrison, Sean J., Liao, Xinsheng, Weissman, Irving L.
Publicado em 1999

TMIC-04. A POTENT MICROGLIAL RESPONSE TO BLOCKING THE CD47-SIRPα ANTI-PHAGOCYTIC AXIS OVERCOMES DEFICIENT MACROPHAGE RECRUITMENT DURING ANTI-CD47 IMMUNOTHERAPY AGAINST GLIOBLASTOMA...

Por Hutter, Gregor, Theruvath, Johanna, Graef, Claus Moritz, Weissman, Irving, Mitra, Siddhartha S, Cheshier, Samuel H
Publicado no Neuro Oncol (2017)

Casein Kinase 2α Regulates Glioblastoma Brain Tumor Initiating Cell Growth through the β-Catenin Pathway

Por Nitta, Ryan T., Gholamin, Sharareh, Feroze, Abdullah H., Agarwal, Maya, Cheshier, Samuel H., Mitra, Siddhartha S., Li, Gordon
Publicado no Oncogene (2014)

Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway

Por Lee, Kyu-Sun, Wu, Zhihao, Song, Yan, Mitra, Siddhartha S., Feroze, Abdullah H., Cheshier, Samuel H., Lu, Bingwei
Publicado em 2013

PM-08 A HUMANIZED CO-TRANSPLANT XENOGRAFT MOUSE MODEL, TO STUDY TOXICITY OF DRUGS TARGETED AGAINST PEDIATRIC BRAIN TUMORS

Por Gholamin, Sharareh, Kahn, Suzana Assad, Esparza, Rogelio, Hutter, Gregor, Feroze, Abdullah, Weissman, Irving L., Mitra, Siddhartha S., Cheshier, Samuel H.
Publicado no Neuro Oncol (2015)

IMMU-45. CHECKPOINT MOLECULE B7-H3 IS HIGHLY EXPRESSED ON MEDULLOBLASTOMA AND PROVES TO BE A PROMISING CANDIDATE FOR CAR T CELL IMMUNOTHERAPY

Por Theruvath, Johanna, Heitzeneder, Sabine, Majzner, Robbie, Cui, Karen, Nellan, Anandani, Graef, Claus Moritz, Cheshier, Samuel H, Mackall, Crystal, Mitra, Siddhartha S
Publicado no Neuro Oncol (2017)

Wnt-mediated self-renewal of neural stem/progenitor cells

Por Kalani, M. Yashar S., Cheshier, Samuel H., Cord, Branden J., Bababeygy, Simon R., Vogel, Hannes, Weissman, Irving L., Palmer, Theo D., Nusse, Roel
Publicado em 2008

Glioblastoma Multiforme: Exploratory Radiogenomic Analysis by Using Quantitative Image Features

Por Gevaert, Olivier, Mitchell, Lex A., Achrol, Achal S., Xu, Jiajing, Echegaray, Sebastian, Steinberg, Gary K., Cheshier, Samuel H., Napel, Sandy, Zaharchuk, Greg, Plevritis, Sylvia K.
Publicado no Radiology (2014)

Glioblastoma Multiforme: Exploratory Radiogenomic Analysis by Using Quantitative Image Features

Por Gevaert, Olivier, Mitchell, Lex A., Achrol, Achal S., Xu, Jiajing, Echegaray, Sebastian, Steinberg, Gary K., Cheshier, Samuel H., Napel, Sandy, Zaharchuk, Greg, Plevritis, Sylvia K.
Publicado no Radiology (2015)

A Bioengineered Peptide that Localizes to and Illuminates Medulloblastoma: A New Tool with Potential for Fluorescence-Guided Surgical Resection

Por Ackerman, Shelley E., Wilson, Christy M., Kahn, Suzana A., Kintzing, James R., Jindal, Darren A., Cheshier, Samuel H., Grant, Gerald A., Cochran, Jennifer R.
Publicado no Cureus (2014)

Brain Tumor Stem Cell Multipotency Correlates with Nanog Expression and Extent of Passaging in Human Glioblastoma Xenografts

Por Higgins, Dominique M., Wang, Ruisi, Milligan, Brian, Schroeder, Mark, Carlson, Brett, Pokorny, Jenny, Cheshier, Samuel H., Meyer, Fredric B., Weissman, Irving L., Sarkaria, Jann N., Henley, John R.
Publicado em 2013

IMMU-49. TARGETING CCR2 SIGNALING IN PEDIATRIC MEDULLOBLASTOMA

Por Bredlau, Amy-Lee, Eskandari, Ramin, Henderson, Fraser, Infinger, Libby Kosnik, McDonald, Daniel G, Vanek, Kenneth N, Patel, Sunil J, Cheshier, Samuel H, Lowe, Stephen, Cachia, David, Das, Arabinda
Publicado no Neuro Oncol (2017)

Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy

Por Zhu, Huaiyang, Leiss, Lina, Yang, Ning, Rygh, Cecilie B., Mitra, Siddhartha S., Cheshier, Samuel H., Weissman, Irving L., Huang, Bin, Miletic, Hrvoje, Bjerkvig, Rolf, Enger, Per Ø., Li, Xingang, Wang, Jian
Publicado no Oncotarget (2017)

Anti-CD47 Treatment Stimulates Phagocytosis of Glioblastoma by M1 and M2 Polarized Macrophages and Promotes M1 Polarized Macrophages In Vivo

Por Zhang, Michael, Hutter, Gregor, Kahn, Suzana A., Azad, Tej D., Gholamin, Sharareh, Xu, Chelsea Y., Liu, Jie, Achrol, Achal S., Richard, Chase, Sommerkamp, Pia, Schoen, Matthew Kenneth, McCracken, Melissa N., Majeti, Ravi, Weissman, Irving, Mitra, Siddhartha S., Cheshier, Samuel H.
Publicado no PLoS One (2016)

Purification and characterization of progenitor and mature human astrocytes reveals transcriptional and functional differences with mouse

Por Zhang, Ye, Sloan, Steven A., Clarke, Laura E., Caneda, Christine, Plaza, Colton A., Blumenthal, Paul D., Vogel, Hannes, Steinberg, Gary K., Edwards, Michael S. B., Li, Gordon, Duncan, John A., Cheshier, Samuel H., Shuer, Lawrence M., Chang, Edward F., Grant, Gerald A., Hayden Gephart, Melanie G., Barres, Ben A.
Publicado no Neuron (2015)

The anti‐hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ‐dependent inhibition of the AKT pathway

Por Assad Kahn, Suzana, Costa, Silvia Lima, Gholamin, Sharareh, Nitta, Ryan T, Dubois, Luiz Gustavo, Fève, Marie, Zeniou, Maria, Coelho, Paulo Lucas Cerqueira, El‐Habr, Elias, Cadusseau, Josette, Varlet, Pascale, Mitra, Siddhartha S, Devaux, Bertrand, Kilhoffer, Marie‐Claude, Cheshier, Samuel H, Moura‐Neto, Vivaldo, Haiech, Jacques, Junier, Marie‐Pierre, Chneiweiss, Hervé
Publicado no EMBO Mol Med (2016)

EPIGENETIC TARGETING OF HEDGEHOG PATHWAY TRANSCRIPTIONAL OUTPUT

Por Cho, Yoon-Jae, Tang, Yujie, Schubert, Simone, Willardson, Minde, Bandopadhayay, Pratiti, Bergthold, Guillame, Nguyen, Brian, Masoud, Sabran, Vue, Nujsaubnusi, Balansay, Brianna, Gholamin, Sharareh, Cheshier, Samuel H., Atwood, Scott X., Whitson, Ramon J., Lee, Alex, Tang, Jean Y., Qi, Jun, Beroukhim, Rameen, Wechsler-Reya, Rob, Oro, Anthony E., Link, Brian, Bradner, James E., Cho, Yoon-Jae
Publicado em 2014

Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition

Por Tang, Yujie, Gholamin, Sharareh, Schubert, Simone, Willardson, Minde I., Lee, Alex, Bandopadhayay, Pratiti, Bergthold, Guillame, Masoud, Sabran, Nguyen, Brian, Vue, Nujsaubnusi, Balansay, Brianna, Yu, Furong, Oh, Sekyung, Woo, Pamelyn, Chen, Spenser, Ponnuswami, Anitha, Monje, Michelle, Atwood, Scott X., Whitson, Ramon J., Mitra, Siddhartha, Cheshier, Samuel H., Qi, Jun, Beroukhim, Rameen, Tang, Jean Y., Wechsler-Reya, Rob, Oro, Anthony E., Link, Brian A., Bradner, James E., Cho, Yoon-Jae
Publicado em 2014

Gpr124 is essential for blood–brain barrier integrity in central nervous system disease

Por Chang, Junlei, Mancuso, Michael R, Maier, Carolina, Liang, Xibin, Yuki, Kanako, Yang, Lu, Kwong, Jeffrey W, Wang, Jing, Rao, Varsha, Vallon, Mario, Kosinski, Cynthia, Zhang, J J Hailing, Mah, Amanda T, Xu, Lijun, Li, Le, Gholamin, Sharareh, Reyes, Teresa F, Li, Rui, Kuhnert, Frank, Han, Xiaoyuan, Yuan, Jenny, Chiou, Shin-Heng, Brettman, Ari D, Daly, Lauren, Corney, David C, Cheshier, Samuel H, Shortliffe, Linda D, Wu, Xiwei, Snyder, Michael, Chan, Pak, Giffard, Rona G, Chang, Howard Y, Andreasson, Katrin, Kuo, Calvin J
Publicado no Nat Med (2017)