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The Role of Apoptosis in the Regulation of Hematopoietic Stem Cells: Overexpression of BCL-2 Increases Both Their Number and Repopulation Potential

Hematopoietic stem cells (HSC) give rise to cells of all hematopoietic lineages, many of which are short lived. HSC face developmental choices: self-renewal (remain an HSC with long-term multilineage repopulating potential) or differentiation (become an HSC with short-term multilineage repopulating...

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Detalles Bibliográficos
Main Authors: Domen, Jos, Cheshier, Samuel H., Weissman, Irving L.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195763/
https://ncbi.nlm.nih.gov/pubmed/10637270
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