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ATRT-25. CHECKPOINT MOLECULE B7-H3 IS HIGHLY EXPRESSED ON ATYPICAL RHABDOID TERATOID TUMOR (ATRT) AND IS A PROMISING CANDIDATE FOR CAR T CELL THERAPY

ATRT are highly malignant brain tumors arising in very young children. The prognosis is extremely poor. Hence new treatments are urgently needed. B7-H3 (CD276) is a member of the B7 family of molecules involved in immune regulation and is over-expressed on a wide variety of solid cancers. We recentl...

詳細記述

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書誌詳細
出版年:Neuro Oncol
主要な著者: Theruvath, Johanna, Graef, Claus-Moritz, Heitzeneder, Sabine, Majzner, Robbie, Mitra, Siddhartha, Cheshier, Samuel H, Mackall, Crystal
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012766/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.023
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