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IMMU-07. CHECKPOINT MOLECULE B7-H3 IS HIGHLY EXPRESSED ON MEDULLOBLASTOMA AND PROVES TO BE A PROMISING CANDIDATE FOR CAR T CELL IMMUNOTHERAPY
BACKGROUND: B7-H3 (CD276) is a member of the B7 family of molecules involved in immune regulation and is over-expressed on a wide variety of solid tumor types. For this study we used a second-generation chimeric antigen receptor (CAR) T-cell targeting B7-H3 with the 41BB using a binder based on anti...
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| Wydane w: | Neuro Oncol |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475088/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.117 |
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