ATRT-25. CHECKPOINT MOLECULE B7-H3 IS HIGHLY EXPRESSED ON ATYPICAL RHABDOID TERATOID TUMOR (ATRT) AND IS A PROMISING CANDIDATE FOR CAR T CELL THERAPY

ATRT are highly malignant brain tumors arising in very young children. The prognosis is extremely poor. Hence new treatments are urgently needed. B7-H3 (CD276) is a member of the B7 family of molecules involved in immune regulation and is over-expressed on a wide variety of solid cancers. We recentl...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Theruvath, Johanna, Graef, Claus-Moritz, Heitzeneder, Sabine, Majzner, Robbie, Mitra, Siddhartha, Cheshier, Samuel H, Mackall, Crystal
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Abstracts
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012766/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.023
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky