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Wnt-mediated self-renewal of neural stem/progenitor cells

In this work we have uncovered a role for Wnt signaling as an important regulator of stem cell self-renewal in the developing brain. We identified Wnt-responsive cells in the subventricular zone of the developing E14.5 mouse brain. Responding cell populations were enriched for self-renewing stem cel...

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Autori principali: Kalani, M. Yashar S., Cheshier, Samuel H., Cord, Branden J., Bababeygy, Simon R., Vogel, Hannes, Weissman, Irving L., Palmer, Theo D., Nusse, Roel
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575225/
https://ncbi.nlm.nih.gov/pubmed/18957545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808616105
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