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Wnt proteins are self-renewing factors for mammary stem cells and promote their long-term expansion in culture

Adult stem cells have the ability to self-renew and to generate specialized cells. Self-renewal is dependent on extrinsic niche factors but few of those signals have been identified. In addition, stem cells tend to differentiate in the absence of the proper signals, and are therefore difficult to ma...

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Bibliografische gegevens
Hoofdauteurs: Zeng, Yi Arial, Nusse, Roel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917779/
https://ncbi.nlm.nih.gov/pubmed/20569694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.03.020
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