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Wnt proteins are self-renewing factors for mammary stem cells and promote their long-term expansion in culture

Adult stem cells have the ability to self-renew and to generate specialized cells. Self-renewal is dependent on extrinsic niche factors but few of those signals have been identified. In addition, stem cells tend to differentiate in the absence of the proper signals, and are therefore difficult to ma...

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Autors principals: Zeng, Yi Arial, Nusse, Roel
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917779/
https://ncbi.nlm.nih.gov/pubmed/20569694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.03.020
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