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Wnt proteins are self-renewing factors for mammary stem cells and promote their long-term expansion in culture

Adult stem cells have the ability to self-renew and to generate specialized cells. Self-renewal is dependent on extrinsic niche factors but few of those signals have been identified. In addition, stem cells tend to differentiate in the absence of the proper signals, and are therefore difficult to ma...

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Autores principales: Zeng, Yi Arial, Nusse, Roel
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917779/
https://ncbi.nlm.nih.gov/pubmed/20569694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.03.020
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