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Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling

The skin is a classical example of a tissue maintained by stem cells. However, the identity of the stem cells that maintain the interfollicular epidermis and the source of the signals that control their activity remain unclear. Using lineage tracing and quantitative clonal analyses, we showed that t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lim, Xinhong, Tan, Si Hui, Koh, Winston Lian Chye, Chau, Rosanna Man Wah, Yan, Kelley S., Kuo, Calvin J., van Amerongen, Renée, Klein, Allon Moshe, Nusse, Roel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081860/
https://ncbi.nlm.nih.gov/pubmed/24311688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1239730
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