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Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease
Prion diseases are fatal, transmissible, neurodegenerative diseases caused by the misfolding of the prion protein (PrP). At present, the molecular pathways underlying prion-mediated neurotoxicity are largely unknown. We hypothesized that the transcriptional regulator of the stress response, heat sho...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533240/ https://ncbi.nlm.nih.gov/pubmed/18757733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806319105 |
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