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SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells
Prnp(−/−) mice lack the prion protein PrP(C) and are resistant to prion infections, but variable phenotypes have been reported in Prnp(−/−) mice and the physiological function of PrP(C) remains poorly understood. Here we examined a cell-autonomous phenotype, inhibition of macrophage phagocytosis of...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832919/ https://ncbi.nlm.nih.gov/pubmed/24145514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131274 |
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