Divergence of imprinted genes during mammalian evolution

Por Hutter, Barbara, Bieg, Matthias, Helms, Volkhard, Paulsen, Martina
Publicado em 2010

Imprinted genes show unique patterns of sequence conservation

Por Hutter, Barbara, Bieg, Matthias, Helms, Volkhard, Paulsen, Martina
Publicado em 2010

Genetic and epigenetic profiling of a solitary Peutz–Jeghers colon polyp

Por Linhart, Heinz, Bormann, Felix, Hutter, Barbara, Brors, Benedikt, Lyko, Frank
Publicado no Cold Spring Harb Mol Case Stud (2017)

Evolution of a FLT3-TKD mutated subclone at meningeal relapse in acute promyelocytic leukemia

Por Bochtler, Tilmann, Fröhling, Stefan, Weichert, Wilko, Endris, Volker, Thiede, Christian, Hutter, Barbara, Hundemer, Michael, Ho, Anthony D., Krämer, Alwin
Publicado no Cold Spring Harb Mol Case Stud (2016)

From somatic variants towards precision oncology: Evidence-driven reporting of treatment options in molecular tumor boards

Por Perera-Bel, Júlia, Hutter, Barbara, Heining, Christoph, Bleckmann, Annalen, Fröhlich, Martina, Fröhling, Stefan, Glimm, Hanno, Brors, Benedikt, Beißbarth, Tim
Publicado no Genome Med (2018)

Coverage Bias and Sensitivity of Variant Calling for Four Whole-genome Sequencing Technologies

Por Rieber, Nora, Zapatka, Marc, Lasitschka, Bärbel, Jones, David, Northcott, Paul, Hutter, Barbara, Jäger, Natalie, Kool, Marcel, Taylor, Michael, Lichter, Peter, Pfister, Stefan, Wolf, Stephan, Brors, Benedikt, Eils, Roland
Publicado em 2013

Successful BRAF/MEK inhibition in a patient with BRAF(V600E)-mutated extrapancreatic acinar cell carcinoma

Por Busch, Elena, Kreutzfeldt, Simon, Agaimy, Abbas, Mechtersheimer, Gunhild, Horak, Peter, Brors, Benedikt, Hutter, Barbara, Fröhlich, Martina, Uhrig, Sebastian, Mayer, Philipp, Schröck, Evelin, Stenzinger, Albrecht, Glimm, Hanno, Jäger, Dirk, Springfeld, Christoph, Fröhling, Stefan, Zschäbitz, Stefanie
Publicado no Cold Spring Harb Mol Case Stud (2020)

TelomereHunter – in silico estimation of telomere content and composition from cancer genomes

Por Feuerbach, Lars, Sieverling, Lina, Deeg, Katharina I., Ginsbach, Philip, Hutter, Barbara, Buchhalter, Ivo, Northcott, Paul A., Mughal, Sadaf S., Chudasama, Priya, Glimm, Hanno, Scholl, Claudia, Lichter, Peter, Fröhling, Stefan, Pfister, Stefan M., Jones, David T. W., Rippe, Karsten, Brors, Benedikt
Publicado no BMC Bioinformatics (2019)

BRAF inhibitor–associated ERK activation drives development of chronic lymphocytic leukemia

Por Yaktapour, Niuscha, Meiss, Frank, Mastroianni, Justin, Zenz, Thorsten, Andrlova, Hana, Mathew, Nimitha R., Claus, Rainer, Hutter, Barbara, Fröhling, Stefan, Brors, Benedikt, Pfeifer, Dietmar, Pantic, Milena, Bartsch, Ingrid, Spehl, Timo S., Meyer, Philipp T., Duyster, Justus, Zirlik, Katja, Brummer, Tilman, Zeiser, Robert
Publicado no J Clin Invest (2014)

Genomic footprints of activated telomere maintenance mechanisms in cancer

Por Sieverling, Lina, Hong, Chen, Koser, Sandra D., Ginsbach, Philip, Kleinheinz, Kortine, Hutter, Barbara, Braun, Delia M., Cortés-Ciriano, Isidro, Xi, Ruibin, Kabbe, Rolf, Park, Peter J., Eils, Roland, Schlesner, Matthias, Brors, Benedikt, Rippe, Karsten, Jones, David T. W., Feuerbach, Lars
Publicado no Nat Commun (2020)

TB-17 A COMPREHENSIVE PAN-CANCER ANALYSIS OF CHILDHOOD MALIGNANCIES

Por Groebner, Susanne N., Worst, Barbara, Jones, David T.W., Buchhalter, Ivo, Kleinheinz, Kortine, Weischenfeldt, Joachim, Johann, Pascal D., Segura-Wang, Maia, Northcott, Paul A., Kool, Marcel, Hutter, Barbara, Bender, Sebastian, Korbel, Jan O., Schlesner, Matthias, Chavez, Lukas, Zapatka, Marc, Lichter, Peter, Pfister, Stefan M.
Publicado no Neuro Oncol (2016)

Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters

Por Behjati Ardakani, Fatemeh, Kattler, Kathrin, Nordström, Karl, Gasparoni, Nina, Gasparoni, Gilles, Fuchs, Sarah, Sinha, Anupam, Barann, Matthias, Ebert, Peter, Fischer, Jonas, Hutter, Barbara, Zipprich, Gideon, Imbusch, Charles D., Felder, Bärbel, Eils, Jürgen, Brors, Benedikt, Lengauer, Thomas, Manke, Thomas, Rosenstiel, Philip, Walter, Jörn, Schulz, Marcel H.
Publicado no Epigenetics Chromatin (2018)

Integration of genomics and histology revises diagnosis and enables effective therapy of refractory cancer of unknown primary with PDL1 amplification

Por Gröschel, Stefan, Bommer, Martin, Hutter, Barbara, Budczies, Jan, Bonekamp, David, Heining, Christoph, Horak, Peter, Fröhlich, Martina, Uhrig, Sebastian, Hübschmann, Daniel, Geörg, Christina, Richter, Daniela, Pfarr, Nicole, Pfütze, Katrin, Wolf, Stephan, Schirmacher, Peter, Jäger, Dirk, von Kalle, Christof, Brors, Benedikt, Glimm, Hanno, Weichert, Wilko, Stenzinger, Albrecht, Fröhling, Stefan
Publicado no Cold Spring Harb Mol Case Stud (2016)

Response to olaparib in a PALB2 germline mutated prostate cancer and genetic events associated with resistance

Por Horak, Peter, Weischenfeldt, Joachim, von Amsberg, Gunhild, Beyer, Burkhard, Schütte, Andreas, Uhrig, Sebastian, Gieldon, Laura, Klink, Barbara, Feuerbach, Lars, Hübschmann, Daniel, Kreutzfeldt, Simon, Heining, Christoph, Maier, Sebastian, Hutter, Barbara, Penzel, Roland, Schlesner, Matthias, Eils, Roland, Sauter, Guido, Stenzinger, Albrecht, Brors, Benedikt, Schröck, Evelin, Glimm, Hanno, Fröhling, Stefan, Schlomm, Thorsten
Publicado no Cold Spring Harb Mol Case Stud (2019)

ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing

Por Jäger, Natalie, Jones, David TW, Kool, Marcel, Zichner, Thomas, Hutter, Barbara, Sultan, Marc, Cho, Yoon-Jae, Pugh, Trevor J, Hovestadt, Volker, Stütz, Adrian M, Rausch, Tobias, Warnatz, Hans-Jörg, Brors, Benedikt, Northcott, Paul A, Taylor, Michael D, Meyerson, Matthew, Pomeroy, Scott L, Yaspo, Marie-Laure, Korbel, Jan O, Korshunov, Andrey, Eils, Roland, Pfister, Stefan M, Lichter, Peter
Publicado em 2012

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction

Por Schmidt, Florian, Gasparoni, Nina, Gasparoni, Gilles, Gianmoena, Kathrin, Cadenas, Cristina, Polansky, Julia K., Ebert, Peter, Nordström, Karl, Barann, Matthias, Sinha, Anupam, Fröhler, Sebastian, Xiong, Jieyi, Dehghani Amirabad, Azim, Behjati Ardakani, Fatemeh, Hutter, Barbara, Zipprich, Gideon, Felder, Bärbel, Eils, Jürgen, Brors, Benedikt, Chen, Wei, Hengstler, Jan G., Hamann, Alf, Lengauer, Thomas, Rosenstiel, Philip, Walter, Jörn, Schulz, Marcel H.
Publicado no Nucleic Acids Res (2017)

Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer

Por Ishaque, Naveed, Abba, Mohammed L., Hauser, Christine, Patil, Nitin, Paramasivam, Nagarajan, Huebschmann, Daniel, Leupold, Jörg Hendrik, Balasubramanian, Gnana Prakash, Kleinheinz, Kortine, Toprak, Umut H., Hutter, Barbara, Benner, Axel, Shavinskaya, Anna, Zhou, Chan, Gu, Zuguang, Kerssemakers, Jules, Marx, Alexander, Moniuszko, Marcin, Kozlowski, Miroslaw, Reszec, Joanna, Niklinski, Jacek, Eils, Jürgen, Schlesner, Matthias, Eils, Roland, Brors, Benedikt, Allgayer, Heike
Publicado no Nat Commun (2018)

Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors

Por Ronellenfitsch, Michael W., Harter, Patrick N., Kirchner, Martina, Heining, Christoph, Hutter, Barbara, Gieldon, Laura, Schittenhelm, Jens, Schuhmann, Martin U., Tatagiba, Marcos, Marquardt, Gerhard, Wagner, Marlies, Endris, Volker, Brandts, Christian H., Mautner, Victor-Felix, Schröck, Evelin, Weichert, Wilko, Brors, Benedikt, von Deimling, Andreas, Mittelbronn, Michel, Steinbach, Joachim P., Reuss, David E., Glimm, Hanno, Stenzinger, Albrecht, Fröhling, Stefan
Publicado no J Clin Invest (2020)

The landscape of chromothripsis across adult cancer types

Por Voronina, Natalia, Wong, John K. L., Hübschmann, Daniel, Hlevnjak, Mario, Uhrig, Sebastian, Heilig, Christoph E., Horak, Peter, Kreutzfeldt, Simon, Mock, Andreas, Stenzinger, Albrecht, Hutter, Barbara, Fröhlich, Martina, Brors, Benedikt, Jahn, Arne, Klink, Barbara, Gieldon, Laura, Sieverling, Lina, Feuerbach, Lars, Chudasama, Priya, Beck, Katja, Kroiss, Matthias, Heining, Christoph, Möhrmann, Lino, Fischer, Andrea, Schröck, Evelin, Glimm, Hanno, Zapatka, Marc, Lichter, Peter, Fröhling, Stefan, Ernst, Aurélie
Publicado no Nat Commun (2020)

Hypermutation of the Inactive X Chromosome Is a Frequent Event in Cancer

Por Jäger, Natalie, Schlesner, Matthias, Jones, David T.W., Raffel, Simon, Mallm, Jan-Philipp, Junge, Kristin M., Weichenhan, Dieter, Bauer, Tobias, Ishaque, Naveed, Kool, Marcel, Northcott, Paul A., Korshunov, Andrey, Drews, Ruben M., Koster, Jan, Versteeg, Rogier, Richter, Julia, Hummel, Michael, Mack, Stephen C., Taylor, Michael D., Witt, Hendrik, Swartman, Benedict, Schulte-Bockholt, Dietrich, Sultan, Marc, Yaspo, Marie-Laure, Lehrach, Hans, Hutter, Barbara, Brors, Benedikt, Wolf, Stephan, Plass, Christoph, Siebert, Reiner, Trumpp, Andreas, Rippe, Karsten, Lehmann, Irina, Lichter, Peter, Pfister, Stefan M., Eils, Roland
Publicado em 2013