Successful BRAF/MEK inhibition in a patient with BRAF(V600E)-mutated extrapancreatic acinar cell carcinoma

Pancreatic acinar cell carcinoma (PAC) is a rare disease with a poor prognosis. Treatment options for metastatic PAC are limited and often follow chemotherapeutic regimens for pancreatic ductal adenocarcinoma. Although recurrent genomic alterations, such as BRAF fusions and defects in genes involved...

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Bibliographic Details
Published in:Cold Spring Harb Mol Case Stud
Main Authors: Busch, Elena, Kreutzfeldt, Simon, Agaimy, Abbas, Mechtersheimer, Gunhild, Horak, Peter, Brors, Benedikt, Hutter, Barbara, Fröhlich, Martina, Uhrig, Sebastian, Mayer, Philipp, Schröck, Evelin, Stenzinger, Albrecht, Glimm, Hanno, Jäger, Dirk, Springfeld, Christoph, Fröhling, Stefan, Zschäbitz, Stefanie
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2020
Subjects:
Research Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476408/
https://ncbi.nlm.nih.gov/pubmed/32843432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a005553
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