Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations

BACKGROUND: Soft-tissue sarcomas (STS) are a heterogeneous group of mesenchymal tumors for which response to immunotherapies is not well established. Therefore, it is important to risk-stratify and identify STS patients who will most likely benefit from these treatments. RESULTS: To reveal shared an...

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Vydáno v:J Transl Med
Hlavní autoři: Simon, Malte, Mughal, Sadaf S., Horak, Peter, Uhrig, Sebastian, Buchloh, Jonas, Aybey, Bogac, Stenzinger, Albrecht, Glimm, Hanno, Fröhling, Stefan, Brors, Benedikt, Imbusch, Charles D.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117561/
https://ncbi.nlm.nih.gov/pubmed/33980253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02858-7
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