Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors

BACKGROUND: Neurofibroma/schwannoma hybrid nerve sheath tumors (N/S HNSTs) are neoplasms associated with larger nerves that occur sporadically and in the context of schwannomatosis or neurofibromatosis type 2 or 1. Clinical management of N/S HNSTs is challenging, especially for large tumors, and est...

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Publicat a:J Clin Invest
Autors principals: Ronellenfitsch, Michael W., Harter, Patrick N., Kirchner, Martina, Heining, Christoph, Hutter, Barbara, Gieldon, Laura, Schittenhelm, Jens, Schuhmann, Martin U., Tatagiba, Marcos, Marquardt, Gerhard, Wagner, Marlies, Endris, Volker, Brandts, Christian H., Mautner, Victor-Felix, Schröck, Evelin, Weichert, Wilko, Brors, Benedikt, von Deimling, Andreas, Mittelbronn, Michel, Steinbach, Joachim P., Reuss, David E., Glimm, Hanno, Stenzinger, Albrecht, Fröhling, Stefan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Clinical Medicine
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190903/
https://ncbi.nlm.nih.gov/pubmed/32017710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130787
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