Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors

BACKGROUND: Neurofibroma/schwannoma hybrid nerve sheath tumors (N/S HNSTs) are neoplasms associated with larger nerves that occur sporadically and in the context of schwannomatosis or neurofibromatosis type 2 or 1. Clinical management of N/S HNSTs is challenging, especially for large tumors, and est...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Ronellenfitsch, Michael W., Harter, Patrick N., Kirchner, Martina, Heining, Christoph, Hutter, Barbara, Gieldon, Laura, Schittenhelm, Jens, Schuhmann, Martin U., Tatagiba, Marcos, Marquardt, Gerhard, Wagner, Marlies, Endris, Volker, Brandts, Christian H., Mautner, Victor-Felix, Schröck, Evelin, Weichert, Wilko, Brors, Benedikt, von Deimling, Andreas, Mittelbronn, Michel, Steinbach, Joachim P., Reuss, David E., Glimm, Hanno, Stenzinger, Albrecht, Fröhling, Stefan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2020
Aiheet:
Clinical Medicine
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190903/
https://ncbi.nlm.nih.gov/pubmed/32017710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130787
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