Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors

BACKGROUND: Neurofibroma/schwannoma hybrid nerve sheath tumors (N/S HNSTs) are neoplasms associated with larger nerves that occur sporadically and in the context of schwannomatosis or neurofibromatosis type 2 or 1. Clinical management of N/S HNSTs is challenging, especially for large tumors, and est...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Ronellenfitsch, Michael W., Harter, Patrick N., Kirchner, Martina, Heining, Christoph, Hutter, Barbara, Gieldon, Laura, Schittenhelm, Jens, Schuhmann, Martin U., Tatagiba, Marcos, Marquardt, Gerhard, Wagner, Marlies, Endris, Volker, Brandts, Christian H., Mautner, Victor-Felix, Schröck, Evelin, Weichert, Wilko, Brors, Benedikt, von Deimling, Andreas, Mittelbronn, Michel, Steinbach, Joachim P., Reuss, David E., Glimm, Hanno, Stenzinger, Albrecht, Fröhling, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190903/
https://ncbi.nlm.nih.gov/pubmed/32017710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130787
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