Pizotifen Activates ERK and Provides Neuroprotection in vitro and in vivo in Models of Huntington’s Disease

著者: Sarantos, Melissa R., Papanikolaou, Theodora, Ellerby, Lisa M., Hughes, Robert E.
出版事項 2012

DEPTOR Is a Stemness Factor That Regulates Pluripotency of Embryonic Stem Cells

著者: Agrawal, Pooja, Reynolds, Joseph, Chew, Shereen, Lamba, Deepak A., Hughes, Robert E.
出版年 J Biol Chem (2014)

Mutant Huntingtin Alters Cell Fate in Response to Microtubule Depolymerization via the GEF-H1-RhoA-ERK Pathway

著者: Varma, Hemant, Yamamoto, Ai, Sarantos, Melissa R., Hughes, Robert E., Stockwell, Brent R.
出版事項 2010

Ubiquitin-specific Peptidase 9, X-linked (USP9X) Modulates Activity of Mammalian Target of Rapamycin (mTOR)

著者: Agrawal, Pooja, Chen, Yu-Ting, Schilling, Birgit, Gibson, Bradford W., Hughes, Robert E.
出版事項 2012

Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR).

著者: Agrawal, Pooja, Chen, Yu-Ting, Schilling, Birgit, Gibson, Bradford W., Hughes, Robert E.
出版事項 2014

A Protein Interaction Network for Ecm29 Links the 26 S Proteasome to Molecular Motors and Endosomal Components

著者: Gorbea, Carlos, Pratt, Gregory, Ustrell, Vicença, Bell, Russell, Sahasrabudhe, Sudhir, Hughes, Robert E., Rechsteiner, Martin
出版事項 2010

Genomic Analysis of ATP Efflux in Saccharomyces cerevisiae

著者: Peters, Theodore W., Miller, Aaron W., Tourette, Cendrine, Agren, Hannah, Hubbard, Alan, Hughes, Robert E.
出版年 G3 (Bethesda) (2015)

Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening

著者: Orr, Adam L., Ashok, Deepthi, Sarantos, Melissa R., Shi, Tong, Hughes, Robert E., Brand, Martin D.
出版年 Free Radic Biol Med (2013)

A Large Scale Huntingtin Protein Interaction Network Implicates Rho GTPase Signaling Pathways in Huntington Disease

著者: Tourette, Cendrine, Li, Biao, Bell, Russell, O'Hare, Shannon, Kaltenbach, Linda S., Mooney, Sean D., Hughes, Robert E.
出版事項 2014

Altered transcription in yeast expressing expanded polyglutamine

著者: Hughes, Robert E., Lo, Russell S., Davis, Colleen, Strand, Andrew D., Neal, Cassandra L., Olson, James M., Fields, Stanley
出版事項 2001

Interaction of an atypical Plasmodium falciparum ETRAMP with human apolipoproteins

著者: Vignali, Marissa, McKinlay, Anastasia, LaCount, Douglas J, Chettier, Rakesh, Bell, Russell, Sahasrabudhe, Sudhir, Hughes, Robert E, Fields, Stanley
出版事項 2008

Novel Inhibitors of Mitochondrial sn-Glycerol 3-phosphate Dehydrogenase

著者: Orr, Adam L., Ashok, Deepthi, Sarantos, Melissa R., Ng, Ryan, Shi, Tong, Gerencser, Akos A., Hughes, Robert E., Brand, Martin D.
出版事項 2014

A Human Protein Interaction Network Shows Conservation of Aging Processes between Human and Invertebrate Species

著者: Bell, Russell, Hubbard, Alan, Chettier, Rakesh, Chen, Di, Miller, John P., Kapahi, Pankaj, Tarnopolsky, Mark, Sahasrabuhde, Sudhir, Melov, Simon, Hughes, Robert E.
出版事項 2009

Natural Genetic Variation in Yeast Reveals That NEDD4 Is a Conserved Modifier of Mutant Polyglutamine Aggregation

著者: Peters, Theodore W., Nelson, Christopher S., Gerencser, Akos A., Dumas, Kathleen J., Tavshanjian, Brandon, Chang, Kyu Chul, Lithgow, Gordon J., Hughes, Robert E.
出版年 G3 (Bethesda) (2018)

Chemical activation of a food deprivation signal extends lifespan

著者: Lucanic, Mark, Garrett, Theo, Yu, Ivan, Calahorro, Fernando, Asadi Shahmirzadi, Azar, Miller, Aaron, Gill, Matthew S., Hughes, Robert E., Holden‐Dye, Lindy, Lithgow, Gordon J.
出版年 Aging Cell (2016)

Tor1 regulates protein solubility in Saccharomyces cerevisiae

著者: Peters, Theodore W., Rardin, Matthew J., Czerwieniec, Gregg, Evani, Uday S., Reis-Rodrigues, Pedro, Lithgow, Gordon J., Mooney, Sean D., Gibson, Bradford W., Hughes, Robert E.
出版事項 2012

Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan

著者: Reis-Rodrigues, Pedro, Czerwieniec, Gregg, Peters, Theodore W, Evani, Uday S, Alavez, Silvestre, Gaman, Emily A, Vantipalli, Maithili, Mooney, Sean D, Gibson, Bradford W, Lithgow, Gordon J, Hughes, Robert E
出版事項 2012

Matrix Metalloproteinases are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington’s Disease

著者: Miller, John P., Holcomb, Jennifer, Al-Ramahi, Ismael, de Haro, Maria, Gafni, Juliette, Zhang, Ningzhe, Kim, Eugene, Sanhueza, Mario, Torcassi, Cameron, Kwak, Seung, Botas, Juan, Hughes, Robert E., Ellerby, Lisa M.
出版事項 2010

Glucocorticoids Suppress Selected Components of the Senescence-Associated Secretory Phenotype

著者: Laberge, Remi-Martin, Zhou, Lili, Sarantos, Melissa R., Rodier, Francis, Freund, Adam, de Keizer, Peter L.J., Liu, Su, Demaria, Marco, Cong, Yu-Sheng, Kapahi, Pankaj, Desprez, Pierre-Yves, Hughes, Robert E., Campisi, Judith
出版事項 2012

A Genome-Scale RNA–Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease

著者: Miller, John P., Yates, Bridget E., Al-Ramahi, Ismael, Berman, Ari E., Sanhueza, Mario, Kim, Eugene, de Haro, Maria, DeGiacomo, Francesco, Torcassi, Cameron, Holcomb, Jennifer, Gafni, Juliette, Mooney, Sean D., Botas, Juan, Ellerby, Lisa M., Hughes, Robert E.
出版事項 2012