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Altered transcription in yeast expressing expanded polyglutamine
Expanded polyglutamine tracts are responsible for at least eight fatal neurodegenerative diseases. In mouse models, proteins with expanded polyglutamine cause transcriptional dysregulation before onset of symptoms, suggesting that this dysregulation may be an early event in polyglutamine pathogenesi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC60848/ https://ncbi.nlm.nih.gov/pubmed/11687606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191498198 |
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