Altered transcription in yeast expressing expanded polyglutamine
Expanded polyglutamine tracts are responsible for at least eight fatal neurodegenerative diseases. In mouse models, proteins with expanded polyglutamine cause transcriptional dysregulation before onset of symptoms, suggesting that this dysregulation may be an early event in polyglutamine pathogenesi...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60848/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11687606/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.191498198 |
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