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Oligomeric and polymeric aggregates formed by proteins containing expanded polyglutamine

Neurological diseases resulting from proteins containing expanded polyglutamine (polyQ) are characteristically associated with insoluble neuronal inclusions, usually intranuclear, and neuronal death. We describe here oligomeric and polymeric aggregates formed in cells by expanded polyQ. These aggreg...

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Detalhes bibliográficos
Main Authors: Iuchi, S., Hoffner, G., Verbeke, P., Djian, P., Green, H.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151354/
https://ncbi.nlm.nih.gov/pubmed/12591956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437660100
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