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Oligomeric and polymeric aggregates formed by proteins containing expanded polyglutamine

Neurological diseases resulting from proteins containing expanded polyglutamine (polyQ) are characteristically associated with insoluble neuronal inclusions, usually intranuclear, and neuronal death. We describe here oligomeric and polymeric aggregates formed in cells by expanded polyQ. These aggreg...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Iuchi, S., Hoffner, G., Verbeke, P., Djian, P., Green, H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151354/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12591956/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437660100
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