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Oligomeric and polymeric aggregates formed by proteins containing expanded polyglutamine

Neurological diseases resulting from proteins containing expanded polyglutamine (polyQ) are characteristically associated with insoluble neuronal inclusions, usually intranuclear, and neuronal death. We describe here oligomeric and polymeric aggregates formed in cells by expanded polyQ. These aggreg...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Iuchi, S., Hoffner, G., Verbeke, P., Djian, P., Green, H.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151354/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12591956/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437660100
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