Altered transcription in yeast expressing expanded polyglutamine

Expanded polyglutamine tracts are responsible for at least eight fatal neurodegenerative diseases. In mouse models, proteins with expanded polyglutamine cause transcriptional dysregulation before onset of symptoms, suggesting that this dysregulation may be an early event in polyglutamine pathogenesi...

Description complète

Détails bibliographiques

Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Hughes, Robert E., Lo, Russell S., Davis, Colleen, Strand, Andrew D., Neal, Cassandra L., Olson, James M., Fields, Stanley
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2001
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60848/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11687606/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.191498198
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!