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Altered transcription in yeast expressing expanded polyglutamine
Expanded polyglutamine tracts are responsible for at least eight fatal neurodegenerative diseases. In mouse models, proteins with expanded polyglutamine cause transcriptional dysregulation before onset of symptoms, suggesting that this dysregulation may be an early event in polyglutamine pathogenesi...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC60848/ https://ncbi.nlm.nih.gov/pubmed/11687606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191498198 |
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