Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor

Spinobulbar muscular atrophy and Huntington's disease are caused by polyglutamine expansion in the androgen receptor and huntingtin, respectively, and their pathogenesis has been associated with abnormal nuclear localization and aggregation of truncated forms of these proteins. Here we show, in...

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Библиографические подробности
Главные авторы: Diamond, Marc I., Robinson, Melissa R., Yamamoto, Keith R.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2000
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC15386/
https://ncbi.nlm.nih.gov/pubmed/10639135
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