Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans
Expansion of polyglutamine repeats in several unrelated proteins causes neurodegenerative diseases with distinct but related pathologies. To provide a model system for investigating common pathogenic features, we have examined the behavior of polyglutamine expansions expressed in Caenorhabditis eleg...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18505/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811890/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100107297 |
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