Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron
The effect of expressing human huntingtin fragments containing polyglutamine (polyQ) tracts of varying lengths was assessed in Caenorhabditis elegans ASH sensory neurons in young and old animals. Expression of a huntingtin fragment containing a polyQ tract of 150 residues (Htn-Q150) led to progressi...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9874792/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.1.179 |
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