Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor
Spinobulbar muscular atrophy and Huntington's disease are caused by polyglutamine expansion in the androgen receptor and huntingtin, respectively, and their pathogenesis has been associated with abnormal nuclear localization and aggregation of truncated forms of these proteins. Here we show, in dive...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15386/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.2.657 |
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