Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor
Spinobulbar muscular atrophy and Huntington's disease are caused by polyglutamine expansion in the androgen receptor and huntingtin, respectively, and their pathogenesis has been associated with abnormal nuclear localization and aggregation of truncated forms of these proteins. Here we show, in dive...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2000
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15386/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.2.657 |
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