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Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates
A hallmark of most neurodegenerative diseases, including those caused by polyglutamine expansion, is the formation of ubiquitin (Ub)-positive protein aggregates in affected neurons. This finding suggests that the Ub system may be involved in common mechanisms underlying these otherwise unrelated dis...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166409/ https://ncbi.nlm.nih.gov/pubmed/12857950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1530212100 |
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