Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates
A hallmark of most neurodegenerative diseases, including those caused by polyglutamine expansion, is the formation of ubiquitin (Ub)-positive protein aggregates in affected neurons. This finding suggests that the Ub system may be involved in common mechanisms underlying these otherwise unrelated dis...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166409/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12857950/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1530212100 |
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