Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates
A hallmark of most neurodegenerative diseases, including those caused by polyglutamine expansion, is the formation of ubiquitin (Ub)-positive protein aggregates in affected neurons. This finding suggests that the Ub system may be involved in common mechanisms underlying these otherwise unrelated dis...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166409/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12857950/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1530212100 |
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