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Pizotifen Activates ERK and Provides Neuroprotection in vitro and in vivo in Models of Huntington’s Disease

BACKGROUND: Huntington’s disease (HD) is a dominantly inherited neurodegenerative condition characterized by dysfunction in striatal and cortical neurons. There are currently no approved drugs known to slow the progression of HD. OBJECTIVE: To facilitate the development of therapies for HD, we ident...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sarantos, Melissa R., Papanikolaou, Theodora, Ellerby, Lisa M., Hughes, Robert E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564659/
https://ncbi.nlm.nih.gov/pubmed/23393546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-120033
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