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DEPTOR Is a Stemness Factor That Regulates Pluripotency of Embryonic Stem Cells

The mammalian target of rapamycin (mTOR) pathway regulates stem cell regeneration and differentiation in response to growth factors, nutrients, cellular energetics, and various extrinsic stressors. Inhibition of mTOR activity has been shown to enhance the regenerative potential of pluripotent stem c...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Agrawal, Pooja, Reynolds, Joseph, Chew, Shereen, Lamba, Deepak A., Hughes, Robert E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231659/
https://ncbi.nlm.nih.gov/pubmed/25258312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.565838
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