Novel Inhibitors of Mitochondrial sn-Glycerol 3-phosphate Dehydrogenase

Mitochondrial sn-glycerol 3-phosphate dehydrogenase (mGPDH) is a ubiquinone-linked enzyme in the mitochondrial inner membrane best characterized as part of the glycerol phosphate shuttle that transfers reducing equivalents from cytosolic NADH into the mitochondrial electron transport chain. Despite...

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Main Authors: Orr, Adam L., Ashok, Deepthi, Sarantos, Melissa R., Ng, Ryan, Shi, Tong, Gerencser, Akos A., Hughes, Robert E., Brand, Martin D.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933693/
https://ncbi.nlm.nih.gov/pubmed/24587137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089938
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