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Novel Inhibitors of Mitochondrial sn-Glycerol 3-phosphate Dehydrogenase

Mitochondrial sn-glycerol 3-phosphate dehydrogenase (mGPDH) is a ubiquinone-linked enzyme in the mitochondrial inner membrane best characterized as part of the glycerol phosphate shuttle that transfers reducing equivalents from cytosolic NADH into the mitochondrial electron transport chain. Despite...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Orr, Adam L., Ashok, Deepthi, Sarantos, Melissa R., Ng, Ryan, Shi, Tong, Gerencser, Akos A., Hughes, Robert E., Brand, Martin D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933693/
https://ncbi.nlm.nih.gov/pubmed/24587137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089938
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