Pizotifen Activates ERK and Provides Neuroprotection in vitro and in vivo in Models of Huntington’s Disease

af Sarantos, Melissa R., Papanikolaou, Theodora, Ellerby, Lisa M., Hughes, Robert E.
Udgivet 2012

DEPTOR Is a Stemness Factor That Regulates Pluripotency of Embryonic Stem Cells

af Agrawal, Pooja, Reynolds, Joseph, Chew, Shereen, Lamba, Deepak A., Hughes, Robert E.
Udgivet i J Biol Chem (2014)

Mutant Huntingtin Alters Cell Fate in Response to Microtubule Depolymerization via the GEF-H1-RhoA-ERK Pathway

af Varma, Hemant, Yamamoto, Ai, Sarantos, Melissa R., Hughes, Robert E., Stockwell, Brent R.
Udgivet 2010

Ubiquitin-specific Peptidase 9, X-linked (USP9X) Modulates Activity of Mammalian Target of Rapamycin (mTOR)

af Agrawal, Pooja, Chen, Yu-Ting, Schilling, Birgit, Gibson, Bradford W., Hughes, Robert E.
Udgivet 2012

Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR).

af Agrawal, Pooja, Chen, Yu-Ting, Schilling, Birgit, Gibson, Bradford W., Hughes, Robert E.
Udgivet 2014

A Protein Interaction Network for Ecm29 Links the 26 S Proteasome to Molecular Motors and Endosomal Components

af Gorbea, Carlos, Pratt, Gregory, Ustrell, Vicença, Bell, Russell, Sahasrabudhe, Sudhir, Hughes, Robert E., Rechsteiner, Martin
Udgivet 2010

Genomic Analysis of ATP Efflux in Saccharomyces cerevisiae

af Peters, Theodore W., Miller, Aaron W., Tourette, Cendrine, Agren, Hannah, Hubbard, Alan, Hughes, Robert E.
Udgivet i G3 (Bethesda) (2015)

Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening

af Orr, Adam L., Ashok, Deepthi, Sarantos, Melissa R., Shi, Tong, Hughes, Robert E., Brand, Martin D.
Udgivet i Free Radic Biol Med (2013)

A Large Scale Huntingtin Protein Interaction Network Implicates Rho GTPase Signaling Pathways in Huntington Disease

af Tourette, Cendrine, Li, Biao, Bell, Russell, O'Hare, Shannon, Kaltenbach, Linda S., Mooney, Sean D., Hughes, Robert E.
Udgivet 2014

Altered transcription in yeast expressing expanded polyglutamine

af Hughes, Robert E., Lo, Russell S., Davis, Colleen, Strand, Andrew D., Neal, Cassandra L., Olson, James M., Fields, Stanley
Udgivet 2001

Interaction of an atypical Plasmodium falciparum ETRAMP with human apolipoproteins

af Vignali, Marissa, McKinlay, Anastasia, LaCount, Douglas J, Chettier, Rakesh, Bell, Russell, Sahasrabudhe, Sudhir, Hughes, Robert E, Fields, Stanley
Udgivet 2008

Novel Inhibitors of Mitochondrial sn-Glycerol 3-phosphate Dehydrogenase

af Orr, Adam L., Ashok, Deepthi, Sarantos, Melissa R., Ng, Ryan, Shi, Tong, Gerencser, Akos A., Hughes, Robert E., Brand, Martin D.
Udgivet 2014

A Human Protein Interaction Network Shows Conservation of Aging Processes between Human and Invertebrate Species

af Bell, Russell, Hubbard, Alan, Chettier, Rakesh, Chen, Di, Miller, John P., Kapahi, Pankaj, Tarnopolsky, Mark, Sahasrabuhde, Sudhir, Melov, Simon, Hughes, Robert E.
Udgivet 2009

Natural Genetic Variation in Yeast Reveals That NEDD4 Is a Conserved Modifier of Mutant Polyglutamine Aggregation

af Peters, Theodore W., Nelson, Christopher S., Gerencser, Akos A., Dumas, Kathleen J., Tavshanjian, Brandon, Chang, Kyu Chul, Lithgow, Gordon J., Hughes, Robert E.
Udgivet i G3 (Bethesda) (2018)

Chemical activation of a food deprivation signal extends lifespan

af Lucanic, Mark, Garrett, Theo, Yu, Ivan, Calahorro, Fernando, Asadi Shahmirzadi, Azar, Miller, Aaron, Gill, Matthew S., Hughes, Robert E., Holden‐Dye, Lindy, Lithgow, Gordon J.
Udgivet i Aging Cell (2016)

Tor1 regulates protein solubility in Saccharomyces cerevisiae

af Peters, Theodore W., Rardin, Matthew J., Czerwieniec, Gregg, Evani, Uday S., Reis-Rodrigues, Pedro, Lithgow, Gordon J., Mooney, Sean D., Gibson, Bradford W., Hughes, Robert E.
Udgivet 2012

Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan

af Reis-Rodrigues, Pedro, Czerwieniec, Gregg, Peters, Theodore W, Evani, Uday S, Alavez, Silvestre, Gaman, Emily A, Vantipalli, Maithili, Mooney, Sean D, Gibson, Bradford W, Lithgow, Gordon J, Hughes, Robert E
Udgivet 2012

Matrix Metalloproteinases are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington’s Disease

af Miller, John P., Holcomb, Jennifer, Al-Ramahi, Ismael, de Haro, Maria, Gafni, Juliette, Zhang, Ningzhe, Kim, Eugene, Sanhueza, Mario, Torcassi, Cameron, Kwak, Seung, Botas, Juan, Hughes, Robert E., Ellerby, Lisa M.
Udgivet 2010

Glucocorticoids Suppress Selected Components of the Senescence-Associated Secretory Phenotype

af Laberge, Remi-Martin, Zhou, Lili, Sarantos, Melissa R., Rodier, Francis, Freund, Adam, de Keizer, Peter L.J., Liu, Su, Demaria, Marco, Cong, Yu-Sheng, Kapahi, Pankaj, Desprez, Pierre-Yves, Hughes, Robert E., Campisi, Judith
Udgivet 2012

A Genome-Scale RNA–Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease

af Miller, John P., Yates, Bridget E., Al-Ramahi, Ismael, Berman, Ari E., Sanhueza, Mario, Kim, Eugene, de Haro, Maria, DeGiacomo, Francesco, Torcassi, Cameron, Holcomb, Jennifer, Gafni, Juliette, Mooney, Sean D., Botas, Juan, Ellerby, Lisa M., Hughes, Robert E.
Udgivet 2012