Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1

Por Moriishi, Kohji, Huang, David C. S., Cory, Suzanne, Adams, Jerry M.
Publicado em 1999

Gefitinib-Induced Killing of NSCLC Cell Lines Expressing Mutant EGFR Requires BIM and Can Be Enhanced by BH3 Mimetics

Por Cragg, Mark S, Kuroda, Junya, Puthalakath, Hamsa, Huang, David C. S, Strasser, Andreas
Publicado em 2007

Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak

Por Lindqvist, Lisa M., Heinlein, Melanie, Huang, David C. S., Vaux, David L.
Publicado em 2014

Current challenges and novel treatment strategies in double hit lymphomas

Por Anderson, Mary Ann, Tsui, Alpha, Wall, Meaghan, Huang, David C. S., Roberts, Andrew W.
Publicado no Ther Adv Hematol (2016)

Deerpox Virus Encodes an Inhibitor of Apoptosis That Regulates Bak and Bax

Por Banadyga, Logan, Lam, Sing-Chi, Okamoto, Toru, Kvansakul, Marc, Huang, David C., Barry, Michele
Publicado em 2011

FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells

Por Pellegrini, Marc, Bath, Sue, Marsden, Vanessa S., Huang, David C. S., Metcalf, Donald, Harris, Alan W., Strasser, Andreas
Publicado em 2005

Apoptosis and non-inflammatory phagocytosis can be induced by mitochondrial damage without caspases

Por van Delft, Mark F., Smith, Darrin P., Lahoud, Mireille H., Huang, David C.S., Adams, Jerry M.
Publicado em 2009

The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity

Por Hinds, Mark G., Lackmann, Martin, Skea, Gretchen L., Harrison, Penny J., Huang, David C.S., Day, Catherine L.
Publicado em 2003

Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak

Por Uren, Rachel T., Dewson, Grant, Chen, Lin, Coyne, Stephanie C., Huang, David C.S., Adams, Jerry M., Kluck, Ruth M.
Publicado em 2007

Debcl, a Proapoptotic Bcl-2 Homologue, Is a Component of the Drosophila melanogaster Cell Death Machinery

Por Colussi, Paul A., Quinn, Leonie M., Huang, David C.S., Coombe, Michelle, Read, Stuart H., Richardson, Helena, Kumar, Sharad
Publicado em 2000

Sheeppox Virus SPPV14 Encodes a Bcl-2-Like Cell Death Inhibitor That Counters a Distinct Set of Mammalian Proapoptotic Proteins

Por Okamoto, Toru, Campbell, Stephanie, Mehta, Ninad, Thibault, John, Colman, Peter M., Barry, Michele, Huang, David C. S., Kvansakul, Marc
Publicado em 2012

Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L)

Por Huang, David C. S., Hahne, Michael, Schroeter, Michael, Frei, Karl, Fontana, Adriano, Villunger, Andreas, Newton, Kim, Tschopp, Juerg, Strasser, Andreas
Publicado em 1999

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x(L), but not Bcl-2, until displaced by BH3-only proteins

Por Willis, Simon N., Chen, Lin, Dewson, Grant, Wei, Andrew, Naik, Edwina, Fletcher, Jamie I., Adams, Jerry M., Huang, David C.S.
Publicado em 2005

Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands.

Por Day, Catherine L, Puthalakath, Hamsa, Skea, Gretchen, Strasser, Andreas, Barsukov, Igor, Lian, Lu-Yun, Huang, David C S, Hinds, Mark G
Publicado em 2004

Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance

Por Silke, John, Kratina, Tobias, Chu, Diep, Ekert, Paul G., Day, Catherine L., Pakusch, Miha, Huang, David C. S., Vaux, David L.
Publicado em 2005

Pro-Apoptotic Apoptosis Protease–Activating Factor 1 (Apaf-1) Has a Cytoplasmic Localization Distinct from Bcl-2 or Bcl-X(L)

Por Hausmann, George, O'Reilly, Lorraine A., van Driel, Rosemary, Beaumont, Jennifer G., Strasser, Andreas, Adams, Jerry M., Huang, David C.S.
Publicado em 2000

In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive Myc-driven lymphomas

Por Mason, Kylie D., Vandenberg, Cassandra J., Scott, Clare L., Wei, Andrew H., Cory, Suzanne, Huang, David C. S., Roberts, Andrew W.
Publicado em 2008

The Proapoptotic BH3-Only Protein Bim Is Expressed in Hematopoietic, Epithelial, Neuronal, and Germ Cells

Por O’Reilly, Lorraine A., Cullen, Leonie, Visvader, Jane, Lindeman, Geoffrey J., Print, Cris, Bath, Mary L., Huang, David C. S., Strasser, Andreas
Publicado em 2000

MCMV-mediated Inhibition of the Pro-apoptotic Bak Protein Is Required for Optimal In Vivo Replication

Por Fleming, Peter, Kvansakul, Marc, Voigt, Valentina, Kile, Benjamin T., Kluck, Ruth M., Huang, David C. S., Degli-Esposti, Mariapia A., Andoniou, Christopher E.
Publicado em 2013

Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax

Por Fletcher, Jamie I., Meusburger, Sarina, Hawkins, Christine J., Riglar, David T., Lee, Erinna F., Fairlie, W. Douglas, Huang, David C. S., Adams, Jerry M.
Publicado em 2008