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FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells

The role of caspase-8 and its adaptor Fas-associated death domain (FADD) in lymphocyte apoptosis is well defined, but their functions in other hemopoietic lineages are not clear. We were unable to generate transgenic mice expressing dominant inhibitors of FADD or caspase-8 in hemopoietic cells, poss...

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Autors principals: Pellegrini, Marc, Bath, Sue, Marsden, Vanessa S., Huang, David C. S., Metcalf, Donald, Harris, Alan W., Strasser, Andreas
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Hematology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895211/
https://ncbi.nlm.nih.gov/pubmed/15905188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0284
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