FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells

The role of caspase-8 and its adaptor Fas-associated death domain (FADD) in lymphocyte apoptosis is well defined, but their functions in other hemopoietic lineages are not clear. We were unable to generate transgenic mice expressing dominant inhibitors of FADD or caspase-8 in hemopoietic cells, poss...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pellegrini, Marc, Bath, Sue, Marsden, Vanessa S., Huang, David C. S., Metcalf, Donald, Harris, Alan W., Strasser, Andreas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society of Hematology 2005
Pynciau:
Hematopoiesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895211/
https://ncbi.nlm.nih.gov/pubmed/15905188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0284
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