FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells

The role of caspase-8 and its adaptor Fas-associated death domain (FADD) in lymphocyte apoptosis is well defined, but their functions in other hemopoietic lineages are not clear. We were unable to generate transgenic mice expressing dominant inhibitors of FADD or caspase-8 in hemopoietic cells, poss...

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Hlavní autoři: Pellegrini, Marc, Bath, Sue, Marsden, Vanessa S., Huang, David C. S., Metcalf, Donald, Harris, Alan W., Strasser, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Hematology 2005
Témata:
Hematopoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895211/
https://ncbi.nlm.nih.gov/pubmed/15905188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0284
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