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FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells

The role of caspase-8 and its adaptor Fas-associated death domain (FADD) in lymphocyte apoptosis is well defined, but their functions in other hemopoietic lineages are not clear. We were unable to generate transgenic mice expressing dominant inhibitors of FADD or caspase-8 in hemopoietic cells, poss...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pellegrini, Marc, Bath, Sue, Marsden, Vanessa S., Huang, David C. S., Metcalf, Donald, Harris, Alan W., Strasser, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Hematology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895211/
https://ncbi.nlm.nih.gov/pubmed/15905188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0284
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