A cloning method to identify caspases and their regulators in yeast: Identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1

Por Hawkins, Christine J., Wang, Susan L., Hay, Bruce A.
Publicado em 1999

Data on the DNA damaging and mutagenic potential of the BH3-mimetics ABT-263/Navitoclax and TW-37

Por Green, Maja M., Shekhar, Tanmay M., Hawkins, Christine J.
Publicado no Data Brief (2016)

SfDronc, an initiator caspase involved in apoptosis in the fall armyworm Spodoptera frugiperda

Por Huang, Ning, Civciristov, Srgjan, Hawkins, Christine J., Clem, Rollie J.
Publicado em 2013

Inhibition of interleukin 1β-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP

Por Hawkins, Christine J., Uren, Anthony G., Häcker, Georg, Medcalf, Robert L., Vaux, David L.
Publicado em 1996

Diablo Promotes Apoptosis by Removing Miha/Xiap from Processed Caspase 9

Por Ekert, Paul G., Silke, John, Hawkins, Christine J., Verhagen, Anne M., Vaux, David L.
Publicado em 2001

Analysis of the minimal specificity of caspase-2 and identification of Ac-VDTTD-AFC as a caspase-2-selective peptide substrate

Por Kitevska, Tanja, Roberts, Sarah J., Pantaki-Eimany, Delara, Boyd, Sarah E., Scott, Fiona L., Hawkins, Christine J.
Publicado em 2014

IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα

Por Shekhar, Tanmay M., Miles, Mark A., Gupte, Ankita, Taylor, Scott, Tascone, Brianna, Walkley, Carl R., Hawkins, Christine J.
Publicado no Oncotarget (2016)

Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function

Por Scott, Fiona L., Fuchs, Greg J., Boyd, Sarah E., Denault, Jean-Bernard, Hawkins, Christine J., Dequiedt, Franck, Salvesen, Guy S.
Publicado em 2008

The N Terminus of the Vaccinia Virus Protein F1L Is an Intrinsically Unstructured Region That Is Not Involved in Apoptosis Regulation

Por Caria, Sofia, Marshall, Bevan, Burton, Robyn-Lee, Campbell, Stephanie, Pantaki-Eimany, Delara, Hawkins, Christine J., Barry, Michele, Kvansakul, Marc
Publicado no J Biol Chem (2016)

Mature DIABLO/Smac Is Produced by the IMP Protease Complex on the Mitochondrial Inner Membrane

Por Burri, Lena, Strahm, Yvan, Hawkins, Christine J., Gentle, Ian E., Puryer, Michelle A., Verhagen, Anne, Callus, Bernard, Vaux, David, Lithgow, Trevor
Publicado em 2005

The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3– and caspase 9–interacting sites

Por Silke, John, Hawkins, Christine J., Ekert, Paul G., Chew, Joanne, Day, Catherine L., Pakusch, Miha, Verhagen, Anne M., Vaux, David L.
Publicado em 2002

Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die

Por Ekert, Paul G., Read, Stuart H., Silke, John, Marsden, Vanessa S., Kaufmann, Hitto, Hawkins, Christine J., Gerl, Robert, Kumar, Sharad, Vaux, David L.
Publicado em 2004

Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax

Por Fletcher, Jamie I., Meusburger, Sarina, Hawkins, Christine J., Riglar, David T., Lee, Erinna F., Fairlie, W. Douglas, Huang, David C. S., Adams, Jerry M.
Publicado em 2008

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP

Por Silke, John, Ekert, Paul G., Day, Catherine L., Hawkins, Christine J., Baca, Manuel, Chew, Joanne, Pakusch, Miha, Verhagen, Anne M., Vaux, David L.
Publicado em 2001

Caspase Inhibitors of the P35 Family Are More Active When Purified from Yeast than Bacteria

Por Brand, Ingo L., Civciristov, Srgjan, Taylor, Nicole L., Talbo, Gert H., Pantaki-Eimany, Delara, Levina, Vita, Clem, Rollie J., Perugini, Matthew A., Kvansakul, Marc, Hawkins, Christine J.
Publicado em 2012

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα

Por Vince, James E., Chau, Diep, Callus, Bernard, Wong, W. Wei-Lynn, Hawkins, Christine J., Schneider, Pascal, McKinlay, Mark, Benetatos, Christopher A., Condon, Stephen M., Chunduru, Srinivas K., Yeoh, George, Brink, Robert, Vaux, David L., Silke, John
Publicado em 2008