Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function

Caspase-8 is the initiator caspase of the extrinsic apoptosis pathway and also has a role in non-apoptotic physiologies. Identifying endogenous substrates for caspase-8 by using integrated bioinformatics and biological approaches is required to delineate the diverse roles of this caspase. We describ...

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Detalhes bibliográficos
Main Authors: Scott, Fiona L., Fuchs, Greg J., Boyd, Sarah E., Denault, Jean-Bernard, Hawkins, Christine J., Dequiedt, Franck, Salvesen, Guy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443678/
https://ncbi.nlm.nih.gov/pubmed/18458084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800331200
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