Caspase-7 uses RNA to enhance proteolysis of poly(ADP-ribose) polymerase 1 and other RNA-binding proteins

Por Desroches, Alexandre, Denault, Jean-Bernard
Publicado no Proc Natl Acad Sci U S A (2019)

Caspase-7 uses an exosite to promote poly(ADP ribose) polymerase 1 proteolysis

Por Boucher, Dave, Blais, Véronique, Denault, Jean-Bernard
Publicado em 2012

Molecular determinants involved in activation of caspase 7

Por BOUCHER, Dave, BLAIS, Véronique, DRAG, Marcin, DENAULT, Jean-Bernard
Publicado no Biosci Rep (2011)

Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)–mediated inhibition of caspase 9

Por Denault, Jean-Bernard, Eckelman, Brendan P., Shin, Hwain, Pop, Cristina, Salvesen, Guy S.
Publicado em 2007

Activation of caspases-8 and -10 by FLIP(L)

Por Boatright, Kelly M., Deis, Cristina, Denault, Jean-Bernard, Sutherlin, Daniel P., Salvesen, Guy S.
Publicado em 2004

XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs

Por Scott, Fiona L, Denault, Jean-Bernard, Riedl, Stefan J, Shin, Hwain, Renatus, Martin, Salvesen, Guy S
Publicado em 2005

Caspase-mediated proteolysis of the sorting nexin 2 disrupts retromer assembly and potentiates Met/hepatocyte growth factor receptor signaling

Por Duclos, Catherine M, Champagne, Audrey, Carrier, Julie C, Saucier, Caroline, Lavoie, Christine L, Denault, Jean-Bernard
Publicado no Cell Death Discov (2017)

Caspases play in traffic

Por Duclos, Catherine M, Champagne, Audrey, Carrier, Julie C, Saucier, Caroline, Lavoie, Christine L, Denault, Jean-Bernard
Publicado no Cell Death Dis (2017)

Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation

Por Oberst, Andrew, Pop, Cristina, Tremblay, Alexandre G., Blais, Véronique, Denault, Jean-Bernard, Salvesen, Guy S., Green, Douglas R.
Publicado em 2010

Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation.

Por Oberst, Andrew, Pop, Cristina, Tremblay, Alexandre G., Blais, Véronique, Denault, Jean-Bernard, Salvesen, Guy S., Green, Douglas R.
Publicado em 2014

Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function

Por Scott, Fiona L., Fuchs, Greg J., Boyd, Sarah E., Denault, Jean-Bernard, Hawkins, Christine J., Dequiedt, Franck, Salvesen, Guy S.
Publicado em 2008

NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity

Por Gharagozloo, Marjan, Mahmoud, Shaimaa, Simard, Camille, Yamamoto, Kenzo, Bobbala, Diwakar, Ilangumaran, Subburaj, Smith, Matthew D., Lamontagne, Albert, Jarjoura, Samir, Denault, Jean-Bernard, Blais, Véronique, Gendron, Louis, Vilariño-Güell, Carles, Sadovnick, A. Dessa, Ting, Jenny P., Calabresi, Peter A., Amrani, Abdelaziz, Gris, Denis
Publicado no PLoS Biol (2019)